Effective May 25, 2017, a single IRB of record will be used in the ethics review of non-exempt human subjects research protocols funded by the NIH that are carried out at more than one site in the U.S.

NIH will only apply this policy to sites where the same research protocol is being conducted at more than one site; it does not apply to studies that involve more than one site but the sites have different roles in carrying out the research. NIH will grant exceptions to the policy if the use of a single IRB is prohibited by federal, state, or tribal laws. This policy applies to research supported through grants, cooperative agreements, contracts, or the NIH Intramural Research Program. This policy does not apply to career development, research training, or fellowship awards, nor does it apply to non-U.S. sites participating in NIH-funded, multi-site studies.

Additional information can be found on the following websites.

Researchers who are applying for NIH grants will be required to include a plan describing the use of a single IRB that will be selected to serve as the IRB of record for all study sites. Please contact the HRPP with any questions regarding this new policy from NIH.