• IACUC documents (Protocols, Amendments, Annual Reports, etc.) must be submitted by the Principal Investigator.
  • Animal Program Office Staff serve as the conduit between the Committee and Investigators during review.  Submission comments, questions, and revisions are routed to the Animal Program Office (APOffice@oregonstate.edu) and are re-routed to the appropriate individuals.

Upon receipt of a new IACUC submission, a pre-review is performed by Animal Program Office Staff. Pre-review comments may include suggestions for revision, prior to Committee review.  Pre-reviews are typically helpful in reducing time to approval.


  • IACUC submissions that have completed pre-review are provided to IACUC members to allow submissions to be Called to Full Committee review (CFC) at the end of each week.  Committee members must have at least 2 full business days to pre-review submissions prior to review assignment.
  • If there is no call for FCR, the submission enters Designated Member Review (DMR).  Designated Reviewers are assigned by the Chair to review the submission, and all submissions involving potential pain or distress are either pre-reviewed or reviewed by a LARC veterinarian.
  • Designated Reviewers typically complete their evaluations within 1 week of assignment, and any questions or Modifications required to Secure Approval (MSAs) are sent back to the PI for response and/or revision.  There may be more than one cycle of Reviewer questions and PI responses.
  • Designated Reviewers must refer a submission to Full Committee Review if there isn't unanimous agreement about conditions for approval, or if there is a stalemate between the Reviewers and the PI. 
  • The approval date is issued when:
    • all Designated Reviewers approve the protocol
    • all outstanding safety and approval requirements have been met 
  • IACUC Protocol approval letters include annual and final expiration dates.

Please contact Animal Program Staff with any questions about the IACUC review process: