The policies and guidance put forth by the OSU Human Research Protection Program borrow extensively from the best practices of a variety of academic institutions, reflect the advice received from federal regulators, and are informed by input from leaders in research ethics. The information provided on this site builds on ideas freely shared between institutions and exists because of the generosity and collegiality demonstrated by the community of professionals who work in the field of human research protections.

  • I need to modify a previously approved iRIS study; how do I do this in Cayuse? Not all legacy studies were migrated into Cayuse. Please review the information about the transition and migration process here: Cayuse Human Ethics Transition. Email us at with questions.
  • Where can I go for assistance using Cayuse HE? The HRPP has developed several resources to assist researchers with using the Cayuse HE system, including Drop-In Help hours. Please visit our Cayuse Training & Advising page.
  • Can I send a message to the HRPP or my study team members within Cayuse? Cayuse does not support a correspondence feature the way our previous system did, so messages to the HRPP or study team members will need to be sent from your own email program.  
  • Will approved study documents still be stamped? The HRPP will no longer stamp all approved study documents. Only Consent forms for Expedited and Full Board review studies will receive stamps.
  • I completed the application form, but how do I confirm it’s been officially submitted to the IRB for review? To submit an application, both the “COMPLETE SUBMISSION” and the “PI certification” steps must be completed. To verify a study has been certified by the PI, click on the “Awaiting Authorization” box in your dashboard. If the study appears there, it means the PI has not yet certified the application. If you are the PI, click on the study, and then click on the “Certify” button in the upper right side of your screen. 
  • Will the Flex designation still be used for minimal-risk studies? No, the HRPP is no longer utilizing the “Flex” category for new applications; instead, the HRPP reviews an application to first determine whether it qualifies for a category of exempt research, and if ineligible, the study will be reviewed using an Expedited or Full Board review process.
  • (Additional content under development)