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Federal regulations do not distinguish between self-experimentation and the participation of other human subjects in research. If you participate in your own research, you are an enrolled subject. The IRB reviews self-experimentation research for the following reasons:
Applications involving self-experimentation should explain how consent will be obtained from all research participants, including the researcher-participant.
Adapted from Johns Hopkins Medicine and the University of Wisconsin-Madison. Sample researcher-participant consent form (University of Wisconsin-Madison).