Federal Regulations and Other Guidance

Federal Regulations

  • Public Health Service (PHS) – Responsibility of Applicants for Promoting Objectivity in Research for Which PHS Funding is Sought (42 CRF 50, Subpart F)
  • Public Health Service (PHS) – Responsible Prospective Contractors (45 CFR 94 PDF)
  • National Science Foundation (NSF) – Conflict of Interest Policies
  • Food & Drug Administration (FDA) – Financial Disclosure by Clinical Investigators (21 CFR 45)
  • Department of Justice (DOJ) – “Research Independence and Integrity” for CFDA No. 16.560 grants (NIJ’s Research, Evaluation and Development Project Grants Program)

Federal Reports on COI

  • AAMC: Financial Conflicts of Interest in Clinical Research (2008) 
  • AAU: Report on Individual and Institutional Conflict of Interest (2001)
  • DHHS: Financial Relationships and Interests in Research Involving Human Subjects (2004)

Articles about Research COI

Research COI Tutorials